The need to identify new clinical questions and seek best evidence to guide practice during the delivery of care is something all health care clinicians encounter.1,2 Health care information to guide practice changes rapidly, as do standards for care, best practice guidelines, and regulatory standards. Providers (physicians, advanced practice nurses [APRNs], physician assistants), bedside nurses, and other health care clinicians need just-in-time tools to facilitate staying informed of current best evidence. Electronic health record (EHR) platforms often contain clinical decision-support tools to guide practice; however, factors that impact effectiveness of information disseminated this way include clinician trust, alert fatigue, and perceived accuracy of the alert.3-5 Acquiring skills and resources to stay informed of current best evidence is essential in today’s fast paced health care environment.A recent scoping review6 that explored APRN implementation of evidence-based practice (EBP) in routine care found that while nurses believed in EBP and that standardization of care improved outcomes, barriers in practice remain. Barriers found in this study are not new to EBP translation, specifically, perceived lack of time to implement EBP and lack of support from leadership and colleagues to change practice.6,7Multiple strategies are required for APRNs and acute and critical care bedside nurses to remain well informed, allowing for EBP translation during the daily care of patients. First, an individual needs to be a knowledgeable consumer of the evidence. The clinician needs to develop skills and strategies to determine what is rigorous, high-quality evidence to consider for guiding practice, as well as skills to include patient preferences within clinical decisions. Evaluation of evidence occurs through determining the level of evidence and strength of a given study and synthesizing evidence across studies. The level of evidence is most often assessed through a research methodology hierarchy of rigor and quality of the study (eg, absence of bias).7 Synthesizing involves assessing multiple studies to determine if the findings from the research studies, critically reviewed, are congruent and can be used to guide intervention decisions.6,8 Evidence hierarchies, or pyramids, often referred to as level of evidence, are used to determine the strength of the study, based on research methodology. The more rigorous the research methodology, the higher the level of evidence. For example, a meta-analysis of randomized controlled trials is often considered level 1, or the highest rigor, based on research methodology. To determine the quality of the study, multiple tools are available to facilitate learning the skills for reviewing studies for strength and quality; however, the important concept to remember is that not all evidence hierarchies are the same. Thus, the clinician should know which evidence hierarchy is being used when discussing research studies to inform practice.The Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group criteria is used by many national organizations in developing and revising practice guidelines. The goal of the GRADE Working Group9 is to reduce confusion associated with multiple evidence hierarchies and provide a process for synthesis of evidence to guide practice recommendations. Gaining skills in understanding GRADE criteria can facilitate meaningful clinical discussions about best evidence and adoption of guidelines for specific conditions. A brief introductory video is available on the GRADE workgroup website9 that provides an overview of the history and current criteria (www.gradeworkinggroup.org).Being an evidence-based clinician requires developing strategies to stay informed. Having the current best evidence come to your email inbox is both an efficient and effective approach. This column will share only a few strategies, as many more continue to evolve. The key for nurses is locating easily accessible, valid, and reliable resources to help remain current with changing practice guidelines and evolving best practices.For journals you frequently read or wish to be informed of for the latest studies, subscribing to an eTOC that can be delivered to your email inbox is an efficient way to stay abreast of the literature.10 You will be alerted when journals publish a new issue and will receive the table of contents, eTOC, for the latest issue. Subscription can be on a per journal basis at each publisher’s website or multiple journals can be followed by subscribing through JournalTOCs (www.journaltocs.ac.uk/index.php).11 For individual subscriptions, simply go to the publisher website of the journal you want to follow, create an account, and sign up to receive eTOCs (for example, for AACN Advanced Critical Care, visit https://aacnjournals.org/my-account/alerts). Most journals provide this service for free. If you would like to follow multiple journals and manage them in one place, create an account with JournalTOCs and then use the search function to identify journals of interest. Click the checkbox next to the journal title, and it will be saved to your account. You can also indicate your desire to receive email alerts. With a free individual account, you can follow up to 20 journals.PubMed12 offers tools that allow you to stay current with the latest research and evidence. To optimize your use of this national database and search engine, create a National Center for Biotechnology Information (NCBI) account using your internet browser, current releases of Microsoft Edge, ORCID, or your institution’s log-in service. With a PubMed account, you will be able to save search strings on topics related to clinical practice and research interests. Once you enter your search strategy or string on the PubMed main search page, select “Create Alert.” This will save search strings and allow the system to email alerts of new publications that coincide with the search strategy. As the user, you decide how frequently (daily, weekly, monthly) you would like to receive email alerts of new literature that falls within the scope of the saved search. These alerts will be sent to the email associated with the NCBI account. The email account, the search terms, and frequency of the alerts can be edited within the NCBI account. Health science librarians are very skilled in helping clinicians navigate searches within PubMed, creating search strings, and facilitating alert patterns that will not overwhelm the clinician’s inbox with unnecessary emails. A step-by-step tutorial is also available at the National Institutes of Health website.13 Email alerts will contain a summary or abstracts of new articles based on your selection. PubMed alerts are an easy and efficient way to be notified of current articles on fast-changing topics for which you want updated evidence and newly published research studies.Podcasts are digital audio presentations made available through the internet or mobile devices. Many are free, most require registration, and some require membership fees. There are numerous podcasts available that range in average episode duration from 10 minutes to an hour addressing diverse health care topics. The American Association of Critical-Care Nurses provides a podcast series addressing leadership topics and a COVID-19 management series that was developed to support clinicians during the height of the pandemic.14 The Society of Critical Care Medicine provides a wide range of critical care practice–focused podcasts on topics relevant to caring for adult and pediatric populations.15 The JAMA Network offers a variety of podcasts that explore clinical reviews, clinical practice topics, latest research summaries and medical news, and more.16 The site does require registration, but most of their podcasts are free. The European Medical Journal Podcast shares conversations that address health care trends and innovations around the world.17 Many of the podcasts at this site are clinically (disease) focused, but the site also investigates nonclinically focused topics such as the impact of robots in health care. A podcast that explores women leaders in health care, HIT Like a Girl Pod, shares a broad range of topics regarding the impact of women in health care.18 TED Health provides a large variety of health care topic podcasts delivered by experts.19 You do need to join this site and it will individualize suggested podcasts based on your listening choices. An APRN-focused podcast, NP Pulse: The Voice of the Nurse Practitioner, is available to help with role development, research, and leadership.20 Other leading health care organizations also provide podcasts that allow for an easy way to listen and learn while driving to work, exercising, or doing other activities.As digital technology becomes a mainstay in how clinicians search for evidence, numerous mobile health applications (mHealth apps) are emerging to facilitate point-of-care information.4 Ascertaining which mHealth apps to trust can be overwhelming. Researchers who explore the utility of mHealth apps have provided guidance on characteristics to weigh in choosing an app: (1) availability of the app on either Android or iOS; (2) internet connection requirements for use; (3) size of the application (it is recommended that the app be less than 50 MB); (4) frequency of clinical updates; and (5) cost (whether the app is free or has associated subscription fees).5,21-23 A growing number of mHealth apps are associated with leading health care organizations and provide diagnostic and treatment guidance. Other mHealth apps provide pharmacology, clinical practice guidelines (eg, US Preventive Services Task Force, www.uspreventiveservicestaskforce.org/apps; Guideline Central, www.guidelinecentral.com/get-the-app), and learning platforms (ie, physical assessment apps). A recent scoping review of 305 studies demonstrated that the mHealth apps most used in practice included UpToDate, Micromedex, Epocrates, MD Consult, and LexiComp.4 However, more mHealth apps continue to be developed to guide practice based on current best evidence. Thus, when considering an mHealth app, be thoughtful about utility, frequency of use, frequency of updates, and accuracy of the information provided.The digital technology explosion has both improved and complicated clinical practice.1,24 As more digitally competent clinicians enter the health care workforce, it is essential for the nurse to be equally competent in critiquing new evidence to guide practice and to develop strategies to easily access current evidence. A recent systematic review and meta-analysis found that when clinicians use electronic knowledge resources, there was an increased frequency of answering clinical questions, positive benefits to patient care, and increased efficiency in time to find answers.1The key to staying informed is developing systems for accessing reliable evidence to guide practice. In today’s practice, it’s essential for nurses to simplify processes of surfacing new evidence and use digital resources that optimize learning and guide care decisions. Acute and critical care nurses are central to translating current best evidence into practice to optimize care provided to vulnerable patients. Having reliable resources can facilitate meeting the expectation of being an evidence-informed clinician.6,8